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In this Review, we highlight such non-canonical targets in preclinical MS research with a focus on five highly promising areas: oligodendrocytes

It plays a role in several biological functions, including oxygen transport and overall brain health .* Adequate iron intake may help maintain normal cognitive function.* Iron is an essential mineral involved in oxygen transport and energy production.* Maintaining adequate iron levels is important for overall vitality and cognitive function.* If necessary, supplementation (such as with Iron Bisglycinate) may be considered under medical supervision

Ann Rev Physiol 42:97110

In some cases, high doses of iodine from supplements can: Increase TSH levels Decrease thyroid hormone production Potentially trigger or exacerbate autoimmune thyroid conditions Its important to note that the effects of iodine on thyroid function can vary greatly depending on an individuals baseline iodine status and overall thyroid health

Levine and colleagues study showed a 35% reduction in the force generated by diaphragm fibres in patients with severe COPD, indicating a decrease in the contractile properties of diaphragm single fibres (Levine et al., 2003)

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